He will hoping his side improve on their first leg performance when Swansea played the Spaniards off the park at their own Mestalla stadium to the point, the home fans applauded their opponents off the pitch after a 3-0 defeat.
Swansea winger Roland Lamah expects a tough match against a team he is familiar with following his time playing in Spain with Osasuna.
"I know Valencia very well from my time in La Liga. They are a very strong side and they will want to confirm their qualification on Thursday.
"There are a lot of similarities between Valencia and ourselves and I think it will be a great game because both teams love to pass the ball and retention is a big part too.
"I know we won 3-0 out there, but that result is in the past. That has no bearing on Thursday night, and we will have to be at our best if we want to get a good result.
"To qualify for the next stage on Thursday would be great for us, but it will be a very tough night as they are a class outfit."
"There's a good feeling in this camp - the players are all together, and I think you can see that out on the pitch in our performances."
Seven-time French champions Lyon can also advance after a stuttering start to their season under Remi Garde, and the embarrassment of failing to reach the knockout phase will only compound their misery of falling in the final Champions League qualifying round at the hands of Real Sociedad.
They host Group I leaders Real Betis at the Gerland stadium, trailing by two points with Vitoria de Guimaraes a further two back and on the road at Croatia's winless outsiders Rijeka
Alexandre Lacazette has been Lyon's main source of goals in domestic action with six, but their inability to kill off matches came back to haunt them again at the weekend when they were pegged back to 1-1 at home to third from bottom Valenciennes.
English FA Cup winners Wigan will keep their adventure going if they can defeat Zulte Waregem and already qualified Rubin Kazan avoid defeat at home to Slovenia's NK Maribor in Russia.