There was frustration for Premier League side Swansea City in the Europa League who were held to a 1-1 draw by Russian side Kuban Krasnodar in south Wales.
It looked like a beautifully-crafted Michu goal midway through the second half would be enough to give Michael Laudrup's men a third win in as many games in Group A, especially as they had not conceded a goal in the section while their opponents had not scored. But the visitors won a penalty in stoppage time when Senegalese substitute Ibrahima Balde was brought down by goalkeeper Gerhard Tremmel and French former Liverpool forward Djibril Cisse netted from 12 yards.
"It's massively disappointing to be honest," said Swansea captain Neil Taylor. "We weren't at our best. Fair play to them, they gave it everything, but that at the end is a sucker punch."
"I think overall it's a fair result, but of course when you're 1-0 up in injury time...yeah, that's a little frustrating," added Laudrup.
"But I have to say that watching the game overall a draw was a fair result."
Last season's English League Cup winners remain a point clear at the top of the section from Valencia, who romped to a 5-1 home win against St Gallen of Switzerland with Fede Cartabia scoring twice.
Like Swansea, Wigan Athletic drew at home against Russian opponents, although the FA Cup holders came from behind to hold Rubin Kazan 1-1 with Nick Powell cancelling out Aleksandr Prudnikov's opener.
Meanwhile, Serie A side Fiorentina followed up their stunning weekend win against Juventus by keeping up their perfect start in Group E, Spanish winger Joaquin setting them on their way to a 3-0 victory against Romanians Pandurii in Florence.
Eintracht Frankfurt of Germany made it three wins out of three in Group F by beating Israel's Maccabi Tel Aviv 2-0, and there was a much-needed win for Lyon, who beat Croatian side Rijeka 1-0 in Group I after a run of just one win in 12 games in all competitions.
Clement Grenier scored the only goal of the game in the second half and OL are level on five points with Betis, who won 1-0 at home to Vitoria Guimaraes.
Betis' city rivals Sevilla, who won the UEFA Cup in successive years in 2006 and 2007, needed a late equalizer to draw 1-1 with Slovan Liberec of the Czech Republic in Group H.